Erectile dysfunction Treatment & ED
You don't have to accept unreliable erections as "part of aging".


What is the best treatment for ED?
What is the best treatment for ED?
The most effective ED treatment is generally a combination of bioidentical hormone replacement or testosterone replacement, PRF or PRP injections (AKA the PShot or Priapus Shot or E² Shot), Medication, like Cialis and supplements
ED has more than one cause, so we have more than one treatment.
Increased sensitivity for more pleasure
Easier erections
Longer-lasting erections
Better erection quality

ED treatment in Naples, Traverse City & Petoskey
Gain confidence in your erections again.
Erection changes are a normal part of the aging process, but they profoundly affect a man’s confidence both in and outside the bedroom. Slowly declining erection function isn’t only about intercourse – it affects many aspects of self-perception, relationships with sex partners, and how “old” or how “healthy” men feel overall.

Does testosterone replacement help with erectile dysfunction?
Yes and not surprisingly, testosterone replacement is one of the best ways to boost erection function. Bioidentical Testosterone Replacement is the foundation of RegenCen's anti-aging treatment program. Testosterone levels slowly decline after the 20’s, and a lot of other things decline with it: strength, muscle mass, energy, and… erections. Low T weakens all aspects of erections, from how often and how easily they occur to the size and strength of erections. Boosting low testosterone levels improves erections in complex physiologic ways. Not only does testosterone increase sex drive, it also boosts nerve signals to the penis to increase blood flow and sensation. Testosterone replacement for ED is a very successful - about 2/3 of men see good improvement in erections with testosterone replacement. But as with most regenerative treatments, treating ED with two or more therapies gives the best results.
How do the P-Shot and the E2 Shot work?
After a quick in office blood draw, your platelet rich fibrin is prepared. Then the penis is numbed and the PRF is injected which releases growth factors. These injections cause:
- Increased penile blood flow response
- New blood vessel growth
- Improved sensation, leading to easier orgasms
- Larger, longer lasting erections
- Enhanced rigidity and penile girth
- Reliable, full erections and increased sexual confidence and sex drive
Most men notice results in about 2-4 weeks. Results last 6-12 months.
What is the best medication for ED?
Cialis or Tidalafil is one of the best prescription medications for ED. Many of our patients get good erectile improvement with simple regenerative treatments and are able to avoid medication and the side effects entirely.
But because ED has many causes, we have many treatments. Our comprehensive ED program supplements those treatments with conventional and unconventional medications, supplements, vacuum assist devices, and other techniques. Our success rate with nonsurgical ED is high - more than 90% of our ED clients report very good or better improvement after the recommended treatment protocol.
Erectile dysfunction is common in men of all ages.
Erectile dysfunction (ED) affects millions of men in the United States. Many men are embarrassed by the changes to their sexual health and responsiveness, but these issues are a natural occurrence. In fact, the prevalence of ED scales with age, and virtually every man has progressively less erection function beyond their 30s.
Tissues in your penis have balloon-like capabilities: they inflate with increased blood flow during erections, then deflate as the flow reverses. As you age, this “ballooning” effect slowly weakens due to changes in blood vessels which impact the flow. Erections lose rigidity and volume, in turn reducing sensitivity and size, making it tougher to climax, reducing the intensity of orgasms, and sometimes even shrinking the size of full erections.
Most common erectile dysfunction causes
Most common erectile dysfunction causes
Low T, blood flow obstruction, underlying medical conditions, and medication side effects are all common ED causes. Age is the most common cause of erectile dysfunction.
Erections depend on blood vessels acting as valves leading to and from the penis. As men age, this valve-like function deteriorates, so rigidity and reliability of erections slowly declines, starting in the 20s. Testosterone also declines as men age, and this reduces erection function as well. Because of this, some decline in erection function happens to all men as they get older.

Erectile dysfunction treatment: The PShot® vs the E² Shot
Although drug treatments like Viagra and Cialis can help, they don’t work in all cases, and become less effective with time. Modern regenerative treatments gives today’s men more options for treating erectile dysfunction.
At our offices in Petoskey, Traverse City, and Naples, we are experts in the administration of the Priapus Shot® (also known as P-Shot), and we have advanced this treatment through the use of PRF. The original P-Shot improves erections utilizing platelet-rich plasma (PRP), and RegenCen Medical Director Dr. Gustav Lo received training and certification to perform the P-Shot through the inventor, Dr. Charles Runels, in 2018. More recent medical studies showed an even better result using PRF (vs PRP) and we coined the term the “E² Shot.”
In addition to enhanced erection function, increased penile length and girth are a goal for many clients. For increased penile size, our treatment program includes a series of 3 injections spaced 4-6 weeks apart, as well as other treatment modalities.
Best treatment for erectile dysfunction?
There is no single best treatment. It all depends upon what you're willing to try, whether there are any side effects, and whether or not it works for you. Medications like Viagra and Cialis are the most common treatments, but many, many men avoid them due to side effects, lack of spontaneity, or interactions with other medications. Since the vast majority of ED is a natural consequence of aging, anti-aging solutions such as testosterone replacement are very successful.
The PShot® & E² Shot
A Step-by-Step Guide
There is very little preparation needed for The E² Shot. You will have a consultation with Dr. Lo in either our Petoskey, Traverse City, or Naples office to make sure that the treatment is right for you. He’ll discuss your health history, so bring a list of current medications and conditions you're being treated for.
Is medication the best treatment for erectile dysfunction?
Most men with ED try medication first, and many find it to be ineffective for them, or undesirable for a variety of reasons: side effects, difficulties timing the dose properly, or simply wanting to avoid drugs. The E² shot is a great alternative for ED when medications haven’t worked or are undesirable for other reasons. Dr. Gustav Lo treated ED for 30 years in his primary care practice and understands medications like Cialis may need to be included in ED treatment.Testosterone replacement also has a high success rate for men with low T. Replacing testosterone to more youthful levels also has an effect no other treatment can claim: improved libido.
Erectile Dysfunction Frequently Asked Questions
Erectile dysfunction usually happens slowly over a period of years and is probably underreported. Still, it is extremely common, afflicting an estimated 35 million men in the United States. About half of all men aged 40 to 70 have erectile dysfunction.
At RegenCen, Dr. Gustav Lo will perform a complete medical history. Sometimes blood work or other tests are required.
For many patients, testosterone replacement therapy improves a low sex drive for men. Testosterone levels decline in men starting in the 30s.
Dr. Lo has treated many men in their 80’s for erectile dysfunction. You are NOT too old! Remember our goal is to help everyone live their best life and if you feel good after going for an exercise walk or climbing stairs, you are generally healthy enough to enjoy sexual activity. Of course, you should always see your primary physician for overall health maintenance.
At RegenCen, we offer the most effective treatments available on the market today, which are medication therapy, testosterone pellets, and the E² shot or PRF / PRP injections.
Yes! Many men with diabetes have ED and our triple therapy for erectile dysfunction can be very successful.
Text or call us at 231.347.7395 to set up your consultation. Don’t worry, your history and treatment will be performed by Dr. Lo or one of our male Physician Associates.
Platelet-rich fibrin (PRF) comes from your own blood, which we draw from you in-office. PRF has been used for years in the medical field to help accelerate healing and to treat orthopedic conditions like arthritis and tendonitis. PRF is composed of platelets, fibrin, and a small number of white blood cells. Growth factors in the platelets and the fibrin scaffold are believed to be what helps tissue regenerate.
When we inject PRF into your penis, the platelets immediately go to work stimulating regrowth of blood vessels, smooth muscle cells and healthy new tissue, which, in turn, improves sexual response with bigger, more rigid erections. Most men report improvement in both length and girth within a few weeks.
PRF works both immediately and over time. Most patients report improved sensation and responsiveness within days of their injection, with the best overall results around 6 weeks post procedure.
Further research and reading on PRF for erectile dysfunction:
No. It's safe to resume sex immediately, and it will not adversely affect your sexual responsiveness.
PRF is 100% natural because it's from your own blood, reducing or eliminating any risk of reaction. Although any injection procedure has minor risks, complications are rare.
After we draw your blood, we prepare it in a centrifuge. During that time, the doctor numbs your penis, ensuring you won't feel any pain or discomfort from the injection procedure. The entire time in the office is about 30-45 minutes.
Though every patient is different, many men repeat PRF treatments every 6-12 months for ongoing, improved sexual performance and satisfaction.
Yes. PRF is an erection boost that can be used with any medical treatments or as a stand alone erectile enhancement. In fact, tadalafil is often prescribed at the time of the injection to improve blood flow and enhance the regrowth of dormant tissue.
Dr. Lo received his training on the Priapus or P-shot in 2017. The P-shot improves erections utilizing platelet-rich plasma (PRP). Soon after, medical studies showed an even better result when PRF is injected vs PRP and we coined the term the “E² shot.”